Retin-A Cream


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Medically reviewed by: Samuel Maaiah, PharmD

Last updated on August 18, 2021

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.


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How to buy Retin-A Cream (Tretinoin) online?

Retin-A Cream can be ordered online through or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page on

Is a prescription required?

Yes, a valid prescription from your doctor is required. Retin-A Cream is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed , faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90-days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your doctor.

Is it safe to order Retin-A Cream (Tretinoin) from 90-Day Meds?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee.

Retin-A Cream Cost

Average US Retail Price 90-Day Meds Price
Retin-A Cream 0.025%
Tretinoin 0.025%
$180.97 (45g)

How much does Retin-A Cream (Tretinoin) cost?

At, we make sure to keep drug prices low. You can view the Retin-A Cream cost savings above with the price comparison of brand and generic Retin-A Cream between the average U.S. retail price and 90-Day Meds price.

What is the lowest price of Retin-A Cream per unit?

Lowest Price Per Unit: $1.17/unit for generic Retin-A 0.025% Cream

Is this price for Retin-A Cream without insurance?

The prices mentioned are without insurance. Unfortunately, we cannot accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are unable to adjudicate with US insurance providers.

Why is Retin-A Cream cheaper from Canada than from the United States?

The cost of medications ordered from Canada are less because their drug prices are negotiated and regulated. The US is a free market economy which is how the price differs since pharmaceutical suppliers can charge what they consider appropriate for the product. As a result, we can offer lower prices to our patients as we utilize medications from these countries.

Retin-A Cream Coupon

Sorry, we do not have a Retin-A Cream (Tretinoin) coupon at the moment, please check back later.

Yes, Check out the Coupon Section of this page.


Is there a lower cost generic Retin-A Cream available?

Retin-A Cream is available as a generic alternative.

How much cheaper is generic Retin-A Cream?

Generic Retin-A Cream (tretinoin) is $35 cheaper than brand Retin-A cream at a quantity of 30g compared to 50g of brand Retin-A.

What is the difference between brand and generic Retin-A Cream?

There is no difference between generic and brand Retin-A Cream. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

How much does shipping cost?

Standard shipping is free.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill RX

How to refill a prescription?

Refilling your prescription is made easy with 90-Day Meds. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.
Our live chat is also a great place to connect with us to place a refill order while you are on the go. You can also call us and speak to customer support to place a refill.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information


What is Retin-A Cream?

Retin-A is a prescription topical medication that is classified as a retinoid.


What is it used for?

Retin-A is used as a topical formulation used to treat acne vulgaris and other skin conditions.

How does it work?

It decreases the cohesiveness of follicular epithelial cells and stimulates mitotic activity. This action increases cell turnover of follicular epithelial cells and improves acne.


How do I take Retin-A Cream?

Use Retin-A Cream as directed by your doctor. Wash your hands before and after using this medication. Use this medication on dry skin and refrain from washing face or applying makeup for at least one hour. Using more than prescribed of this medication will not make it work faster, the application on the face should be invisible; if it dries and appears flakey it means you are applying too much of this medication.

What dosages are available?

Retin-A Cream is available as a brand 0.01%, 0.025%, and 0.05% formulation and as a generic in 0.025%, 0.05%, and 0.1%.

What is the recommended dosage?

Generally the dose should be once daily at bedtime but take as directed by your doctor.

What is the maximum dosage?

The maximum recommended dosage is 1 application per day.

What if I miss a dose?

If you forget to use the Retin-A Cream, apply a dose as soon as you remember. If it is close to when the next dose should be applied, wait until then and apply a normal dose.


What should you know before you take Retin-A Cream?

Retin-A will make you more susceptible to getting a sunburn, patients should use adequate protection from the sun if they are going to have prolonged exposure.

Retin-A will also make you skin more vulnerable to wind a cold

Side Effects

What are the side effects of Retin-A Cream?

Some common side effects include:

  • Application site pain
  • Erythema
  • Dry Skin
  • Hyperpigmentation of the skin
  • Photosensitivity

Speak to your doctor for a full list of side effects.


Does this medication interact with other drugs, foods, or alcohol?

Using other topical products that can significantly dry your skin should be avoided while using Retin-A Cream.

How should this medication be stored?

Store below 86°F, store in a cool dry container away from direct light, do not freeze.


Store below 86°F, store in a cool dry container away from direct light, do not freeze.

Pharmacist Tips

  • Apply once daily before bedtime or as directed. Your physicians may recommend that you start off by applying the cream every other night as some with sensitive skin can experience significant skin irritation at first.
  • Wash your face every night prior to applying, it is also very important to ensure your face is completely dry prior to applying as the moisture may exacerbate irritation.
  • Utilizing a moisturizer w/sunscreen in the morning after washing your face will help with dryness and irritation, it is important to utilize one that will not aggravate acne.


How long does it take for Retin-A cream to work?

Every patient will respond a little differently to Retin-A but generally patients can notice improvements within about 2 weeks whereas some take about 6 weeks to notice significant effects.

What should I avoid when using Retin-A cream?

Patients should avoid utilizing products with a significant drying effect or cause significant irritation (Alcohol wipes, medicated/abrasive soaps, astringents, spices, or lime). The manufacturer also recommends to avoid using preparations that contain sulfur, resorcinol, or salicylic acid and if you have been using them previously, to let your skin rest before starting Retin-A.

Does Retin-A remove dark spots?

Retin-A works by improving cell turnover and as a result can resolve dark spots and freckles.

Should I apply moisturizer after Retin-A?

After applying Retin-A, you should not wash your face or apply additional products to your face for about an hour. The manufacturer does recommend utilizing a moisturizer that will not exacerbate your acne but for it to be applied the morning after the Retin-A application after you wash your face.


This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs before taking any medication.