Prucalopride Succinate

Select your dosage below to view Motegrity cost and place your order. Save up to 90% and get FREE standard shipping on prescription medication delivered to your door.

Prescription Required

Have questions?

Call 1-800-828-4889 or use chat

90 Day Meds Questions
Select product strength & quantity:
Select product strength & quantity:
Select product strength & quantity:
Select product strength & quantity:
Order Medication Online

Skip Lineups

Order Medication Online

Free Shipping

Order Medication Online

Lowest Prices


Medically reviewed by: Samuel Maaiah, PharmD

Last updated on August 18, 2021

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.


* minimum order of $

Order Online

How to buy Motegrity (Prucalopride) online?

Motegrity (Prucalopride) can be ordered online through or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page on 

Is a prescription required?

Yes, a valid prescription from your doctor is required. Motegrity (Prucalopride) is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your doctor.

Is it safe to order Motegrity (Prucalopride) from 90-Day Meds?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.


Average US Retail Price 90-Day Meds Price
Motegrity 2mg $546.00
(20 tablets)
(28 tablets)

How much does Motegrity (Prucalopride) cost?

At, we make sure to keep drug prices low.

You can view the Motegrity (Prucalopride) cost savings above with the price comparison Motegrity between the average U.S. retail price and 90-Day Meds price.

What is the lowest price of Motegrity (Prucalopride) per unit?

Lowest Price Per Unit: $4.04/unit for Motegrity (Prucalopride) 2mg tablets 

Is this price for Motegrity (Prucalopride) without insurance?

The listed prices above are not including insurance. Unfortunately, we do not accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are unable to adjudicate with US insurance providers.

Why is Motegrity (Prucalopride) cheaper from Canada than from the United States?

Drug prices in Canada and some other countries are negotiated and regulated. The US is a free market economy which is why the price fluctuates since pharmaceutical suppliers can charge what they deem appropriate for the product. As a result, we can offer lower prices to our patients as we utilize medications from these countries. 


Sorry, we do not have a Motegrity (Prucalopride Succinate) coupon at the moment, please check back later.

Yes, Check out the Coupon Section of this page.


Is there a lower cost generic Motegrity (Prucalopride) available?

Motegrity (Prucalopride) is not available as a generic alternative.

How much cheaper is generic Motegrity (Prucalopride)?

There is currently no generic alternative to Motegrity.  

What is the difference between brand and generic Motegrity (Prucalopride)?

Once available on the market, there will be no difference between generic and brand Motegrity. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes.  An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

How much does shipping cost?

Standard shipping is free.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill RX

How to refill a prescription?

Refilling your prescription is made easy with 90-Day Meds. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.
You can also call us at 1-800-828-4889 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information


What is Motegrity (Prucalopride)?

Motegrity (Prucalopride) is a prescription medication that is classified as serotonin 5-HT4 receptor agonist.


What is Motegrity used for?

It is used for the treatment of chronic idiopathic constipation in adults. 

How does it work?

It acts as an agonist at the serotonin type 4 receptor which results in gastrointestinal prokinetic stimulation that increases colonic motility.


How do I take Motegrity (Prucalopride)?

Take Motegrity (Prucalopride) by mouth with or without food as directed by your doctor. 

What dosages are available?

Motegrity (Prucalopride) is only available as a brand in 1mg and 2mg tablets.

What is the recommended dosage?

It is typically dosed 2mg once daily but take as directed by your doctor.

What is the maximum dosage?

The maximum recommended dosage is 2mg/day.

What if I miss a dose?

Take the medication as soon as possible if you have missed a dose. If it is almost time for your next dose, skip the missed dose and return back to your regular schedule. Never double the doses.


What should you know before you take Motegrity (Prucalopride)?

There is limited information with use in pregnancy. Consider the use of appropriate contraception in females of reproductive age.

Caution in renal dysfunction. Dose adjustment may be needed.

  • CrCl 30 mL/min or more: No dose adjustment.
  • CrCl < 30 mL/min: 1 mg/daily 
  • ESRD needing hemodialysis: Avoid use. 

Use may cause fatigue and dizziness. Inform patients about performing tasks requiring mental alertness. 

Can cause diarrhea or severe diarrhea, most often reported to occur during the first week of treatment, resolving within a few days. If persistent diarrhea occurs, stop Motegrity (Prucalopride) and speak to a healthcare provider. 

Suicidal ideation, suicide attempts, and suicide have been reported with use. Monitor patients carefully for any new onset or persistent worsening of depression or development of suicidal thoughts. 

Caution in the elderly population. 

Side Effects

What are the side effects of Motegrity (Prucalopride)?

Some common side effects include:

  • Abdominal pain, nausea, diarrhea, severe diarrhea
  • Headache
  • Abdominal distention, flatulence, vomiting
  • Dizziness

Speak to your doctor for a full list of side effects that apply to you if you are taking Motegrity (Prucalopride).


Does this medication interact with other drugs, foods, or alcohol?

Use with anticholinergic agents or opioid agonists may decrease the therapeutic effect of Motegrity (Prucalopride) (Risk Category C).

This is not a full list of potential drug-drug-interactions. Speak to your doctor if you have any concerns about drug-drug-interactions.


How should this medication be stored?

Motegrity (Prucalopride) should be stored between 20°C to 25°C (68°F to 77°F). Excursions are allowed to be stored between 15°C to 30°C (between 59°F to 86°F)

Pharmacist Tips

  • Diarrhea and severe diarrhea can occur, reported mostly during the first week and should go away after a few days. If it does not, stop Motegrity (Prucalopride) and speak to a healthcare provider. 


Is Motegrity (Prucalopride) an antidepressant?


Is Motegrity (Prucalopride) SSRI?

No. Motegrity (Prucalopride) is a serotonin 5-HT4r receptor agonist. 

Is Motegrity (Prucalopride) a laxative?


Does Motegrity (Prucalopride) cause diarrhea?

Diarrhea is listed as a side effect of Motegrity (Prucalopride), most often reported to occur in the first week of drug administration, subsiding in a few days.

Is Motegrity (Prucalopride) FDA-approved?

Motegrity (Prucalopride) is FDA-approved for the treatment of chronic idiopathic constipation in adults. 


This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs before taking any medication.