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Medically reviewed by: Samuel Maaiah, PharmD

Last updated on August 18, 2021

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.


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How to buy Ampyra (Dalfampridine) online?

Ampyra can be ordered online through or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page on

Is a prescription required?

Yes, a valid prescription from your doctor is required. Ampyra is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your doctor.

Is it safe to order Ampyra (Dalfampridine) from 90-Day Meds?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.


Average US Retail Price 90-Day Meds Price
Ampyra 10mg
(56 tablets)
$2805 $959.00

How much does Ampyra (Dalfampridine) cost?

We only supply the brand name version. The cost of 56 tablets of Ampyra 10 mg is $959.00.

What is the lowest price of Ampyra (Dalfampridine) per unit?

Lowest Price Per Unit: $17.13/unit for generic Ampyra (Dalfampridine) 10mg tablets

Is this price for Ampyra (Dalfampridine) without insurance?

The listed prices are without insurance. Unfortunately, we are not able to process claims through insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are  unable to adjudicate with US insurance providers.

Why is Ampyra (Dalfampridine) cheaper from Canada than from the United States

The cost of medications ordered from Canada are internally controlled and regulated. The US is a free market economy which is why the price differs since pharmaceutical suppliers can charge what they determine is appropriate for the medication. As a result, we can offer lower prices to our patients as we utilize medications from these countries.


Sorry, we do not have a Ampyra (Dalfampridine) coupon at the moment, please check back later.

Yes, Check out the Coupon Section of this page.


Is there a lower cost generic Ampyra (Dalfampridine) available?

Ampyra (Dalfampridine) is available as a generic alternative.

How much cheaper is generic Ampyra (Dalfampridine)?

Generic Ampyra (Dalfampridine) is not available through 90-Day Meds. 

What is the difference between brand and generic Ampyra (Dalfampridine)?

Once available on the market, there will be no difference between generic and brand Ampyra (Dalfampridine). Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation


Is shipping available to the United States?

Yes. Your order will be shipped from Canada to the U.S. within 7 to 10 business days. An email notification will be sent to you once the item has been shipped. There are no standard shipping charges.

How much does shipping cost?

Standard shipping is free.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill RX

How to refill a prescription?

Refilling your prescription is made easy with 90-Day Meds. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.

You can also call us and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information


What is Ampyra?

Ampyra is a potassium channel blocker prescription medication.


What is Ampyra used for?

Ampyra is used to treat patients with multiple sclerosis (MS) to improve walking.


How do I take Ampyra?

You will take a 10 mg 12-hr ER tablet by mouth every 12 hours. The maximum daily dose is 20 mg.

What dosages are available?

Dalfampridine is available as either brand or generic 10 mg 12-hr ER tablets.

What if I miss a dose?

If a dose is missed, do not take extra or double your dose of Dalfampridine.


What should I know before I take Dalfampridine?

Dalfampridine is associated with a dose-dependent risk of seizures. Seizures can occur within days to weeks after starting treatment. Seizures have been reported more frequently in patients without a history of seizures. Dalfampridine should be stopped and not restarted if seizures occur while on the medication.


Renal dysfunction is associated with an increased risk of seizures and other adverse side effects.

Side Effects

What are the side effects of Ampyra?

The most common side effects of Ampyra include:

  • Urinary tract infections
  • Constipation
  • Dyspepsia
  • Nausea
  • Impaired balance
  • Dizziness
  • Headache
  • Insomnia
  • Paresthesia
  • Acute exacerbations of MS
  • Asthenia
  • Back pain
  • Nasopharyngitis
  • Pharyngolaryngeal pain

Speak to your doctor for a full list of side effects that apply to you if you are taking Ampyra


Does Ampyra interact with other medication, alcohol, or food?

Trilaciclib may increase the serum concentration of Dalfampridine and alternatives to this combination should be considered (Risk Category D).


How should Ampyra be stored?

This medication should be stored at 25°C (77°F). Excursions can be stored at 15–30°C (59–86°F).

Pharmacist Tips

  • You should stop the medication and speak to your doctor if you experience any seizures while on this medication.
  • This medicine can be taken with or without food. Do not divide, dissolve, chew, or crush the tablet.

Do not double or take extra if you miss your dose.


Can Ampyra cause kidney problems?

Nephrotoxicity is not listed as a side effect of Ampyra. Kidney dysfunction can increase the risk of side effects, such as seizures, as Ampyra is renally eliminated.

What happens if you take too much Ampyra?

Taking too much Ampyra can increase your risk of seizures.

Can you take Ampyra once a day?

You should take Ampyra 10 mg ER-12hr tablet twice daily, which is the recommended dosing. The tablet is 12-hr not 24-hr ER.

What drug class is Ampyra in?

Ampyra is a 4-aminopyridine.

Is Ampyra a disease-modifying therapy?

No. Ampyra is a symptom-based treatment.


This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs before taking any medication.